Postnatal mouse skeletal-muscle N-glycome

Released N-glycans from skeletal muscle at postnatal days 1, 7, 14 and 21, with three source observations at each age.

Usage

glyhub_GPST000079_N(
  kind = c("curated", "raw"),
  cache_dir = getOption("glyhub.cache_dir", tools::R_user_dir("glyhub", "cache")),
  refresh = FALSE,
  offline = FALSE
)

Format

A glyexp::GlycomicSE with 104 features and 12 observations. The abundance assay is in relative abundance (fraction). rowData has no glycan_structure column because no feature has a supported structural annotation.

Source

GlycoPOST GPST000079. BP_muscles_rawdata_251017_Perse. Study: https://doi.org/10.1074/mcp.ra120.002166. Repository: https://glycopost.glycosmos.org/entry/GPST000079.

Arguments

kind: "curated" returns a data object; "raw" returns the path to a verified source archive. Raw archives are currently available for CPTAC.
cache_dir: Cache directory, defaulting to tools::R_user_dir("glyhub", "cache"). Set option glyhub.cache_dir to change the default.
refresh: Download the pinned resource again, even if cached.
offline: Prohibit downloads; require a verified local resource.

Details

Supplementary Table S5 individual abundance columns are used; derived fold changes, SEMs and group averages are not treated as additional samples. The source isomer identifiers and partial linkage annotations are retained. This matrix supports the study of the digalactose-to-sialic-acid switch during muscle development.

Source-derived compositions and original annotation fields are preserved; unknown linkages are not inferred.

Access

Use glyhub_load("glyhub_GPST000079_N") to load this dataset.