Cornu aspersum mucus N-glycan profiles

Released glycans from adhesive, lubricating and protective snail mucus, measured by glycomic mass spectrometry after per-deuter-O-methylation.

Usage

glyhub_GPST000297_N(
  kind = c("curated", "raw"),
  cache_dir = getOption("glyhub.cache_dir", tools::R_user_dir("glyhub", "cache")),
  refresh = FALSE,
  offline = FALSE
)

Format

A glyexp::GlycomicSE with 24 features and 3 observations. The abundance assay is in relative glycan peak-area percentage. rowData includes a typed glycan_structure column; features without a supported structure are NA.

Source

GlycoPOST GPST000297. Supplementary Table 10 (PDF S47). Study: https://doi.org/10.1038/s41467-023-41094-z. Repository: https://glycopost.glycosmos.org/entry/GPST000297.

Arguments

kind: "curated" returns a data object; "raw" returns the path to a verified source archive. Raw archives are currently available for CPTAC.
cache_dir: Cache directory, defaulting to tools::R_user_dir("glyhub", "cache"). Set option glyhub.cache_dir to change the default.
refresh: Download the pinned resource again, even if cached.
offline: Prohibit downloads; require a verified local resource.

Details

All 25 reported rows of Supplementary Table 10 are retained across three source mucus profiles. Values are the published glycan-peak area percentages. Identical source mass/composition/topology assignments are aligned across samples; conflicting masses or proposed isomers remain distinct. Unreported combinations are missing and no renormalization is applied. Each of the three reported N-glycan profiles totals 100%. Native methyl substituents are preserved separately from analytical derivatization. In Table 10 row 10, the diagram adds an outlined diamond absent from the stated composition; row 11 draws two fucoses while its composition states one. Typed composition and structure remain missing for these two features without removing their quantitative observations.

22 proposed source structures retain unspecified linkages and floating-group uncertainty. Native methyl groups remain explicit. Source composition and structure are missing for conflicting N-glycan assignments rather than selected by assumption.

Access

Use glyhub_load("glyhub_GPST000297_N") to load this dataset.