Fetuin N-glycan peak areas across two instrument sites

Usage

glyhub_GPST000578_N_Fetuin_TwoSites(
  kind = c("curated", "raw"),
  cache_dir = getOption("glyhub.cache_dir", tools::R_user_dir("glyhub", "cache")),
  refresh = FALSE,
  offline = FALSE
)

Format

A glyexp::GlycomicSE with 14 features and 2 observations. The abundance assay is in peak area. rowData includes a typed glycan_structure column; features without a supported structure are NA.

Source

GlycoPOST GPST000578. Figure 4e. Study: https://doi.org/10.1038/s41467-026-73091-3. Repository: https://glycopost.glycosmos.org/entry/GPST000578. Quantitative source: https://media.springernature.com/original/springer-static/esm/art%3A10.1038%2Fs41467-026-73091-3/MediaObjects/41467_2026_73091_MOESM4_ESM.xls.

Arguments

kind: "curated" returns a data object; "raw" returns the path to a verified source archive. Raw archives are currently available for CPTAC.
cache_dir: Cache directory, defaulting to tools::R_user_dir("glyhub", "cache"). Set option glyhub.cache_dir to change the default.
refresh: Download the pinned resource again, even if cached.
offline: Prohibit downloads; require a verified local resource.

Details

Complete 14-feature two-site fetuin source peak-area block. Site 1 and Site 2 remain distinct observations. Their sample identity/pairing is not inferred; accompanying dotp values are retained as quality annotations, not quantitative abundance. Quantitative zeros are represented as NA without imputation or renormalization; original measurements are retained. GlyTouCan identifiers remain the source assignments. Sites refer to laboratories/instruments, not protein glycosylation sites. Figure 4c names Site A (Altis Plus) and Site B (Altis); the workbook labels Site 1 and Site 2 are retained without inferring additional correspondence.

All source GlyTouCan identifiers resolve to WURCS through the official GlyTouCan SPARQL service. Structures are converted with glyparse 0.8.1 and validated with glyrepr 1.1.0, and compositions are derived from the validated structures. No mass-based assignments or new experimental linkage evidence are inferred.

Access

Use glyhub_load("glyhub_GPST000578_N_Fetuin_TwoSites") to load this dataset.