Automatic Normalization — auto_normalize • glyclean

This function automatically applies a deterministic default normalization method based on experiment type. Quality Control (QC) samples are not used to benchmark, select, or report normalization behavior.

Usage

auto_normalize(exp, group_col = "group")

Arguments

exp: A glyexp::GlycomicSE(), glyexp::GlycoproteomicSE(), or SummarizedExperiment::SummarizedExperiment() object.
group_col: The column name in sample_info for groups. Default is "group". Can be NULL when no group information is available.

Value

The normalized input container, with its class preserved.

Details

The automatic strategy uses these defaults:

glycomics: normalize_total_area().
glycoproteomics: normalize_median().
missing or other experiment types: normalize_median().

Examples

library(glyexp)
exp_normed <- auto_normalize(real_experiment)
#> ℹ Normalization method: `normalize_median()`
#> ℹ Reason: default for "glycoproteomics".