Glycan structures can have four possible levels of resolution:
"intact": All monosaccharides are concrete (e.g. "Man", "GlcNAc"), and all linkages are fully determined (e.g. "a2-3", "b1-4").
"partial": All monosaccharides are concrete (e.g. "Man", "GlcNAc"), but some linkage information is missing (e.g. "a2-?").
"topological": All monosaccharides are concrete (e.g. "Man", "GlcNAc"), but the linkage information is completely unknown ("??-?").
"basic": All monosaccharides are generic (e.g. "Hex", "HexNAc"), and the linkage information is completely unknown ("??-?").
Note that in theory you can have a glycan with generic monosaccharides with all linkages determined. For example, "Hex(b1-3)HexNAc(a1-" is a valid glycan structure. But in reality, this is almost impossible, because linkage information is far more difficult to acquire than monosaccharide information. This kind of glycan structure is also assigned to "basic" level.
Arguments
- x
A
glycan_structure()vector.
Examples
structures <- as_glycan_structure(c(
"Gal(b1-3)GalNAc(a1-",
"Gal(b1-?)GalNAc(a1-",
"Gal(??-?)GalNAc(??-",
"Hex(??-?)HexNAc(??-",
"Hex(b1-3)HexNAc(a1-"
))
get_structure_level(structures)
#> [1] "intact" "partial" "topological" "basic" "basic"
